HYPERBARIC OXYGEN THERAPY FOR Autism
It has been postulated that children with autism might benefit from Hyperbaric Oxygen Therapy (HBOT) owing to the potential increase in cerebral perfusion occurring during treatment. Inhalation of above-atmospheric oxygen might result in an elevation of arterial partial pressure of oxygen, leading to increased oxygen delivery to the brain.[1]
Hyperbaric oxygen therapy might also have anti-inflammatory properties due to the reduction of pro-inflammatory cytokines (tumour necrosis factor–α, interferon-γ, and interleukins 1 and 6).[2]
Furthermore, HBOT might improve mitochondrial dysfunction, as well as upregulate the production of antioxidant enzymes.
1. Calvert JW, Cahill J, Zhang JH. Hyperbaric oxygen and cerebral physiology. Neurol Res. 2007;29(2):132–41.
2. Rossignol DA, Bradstreet JJ, Vwwan Dyke K, Schneider C, Freedenfeld SH, O’Hara N, et al. Hyperbaric oxygen treatment in autism spectrum disorders. Med Gas Res. 2012;2(1):16.
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